A Comparison of the Antibacterial and Antifungal Activities of Thiosulfinate Analogues of Allicin

Abstract Allicin (diallylthiosulfinate) is a defence molecule from garlic (Allium sativum L.) with broad antimicrobial activities in the low µM range against Gram-positive and -negative bacteria, including antibiotic resistant strains, and fungi. Allicin reacts with thiol groups and can inactivate e...

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Bibliographic Details
Main Authors: Roman Leontiev, Nils Hohaus, Claus Jacob, Martin C. H. Gruhlke, Alan J. Slusarenko
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25154-9