Shaoyao-Gancao Decoction Ameliorates the Inflammation State in Polycystic Ovary Syndrome Rats via Remodeling Gut Microbiota and Suppressing the TLR4/NF-κB Pathway

Shaoyao-Gancao Decoction Ameliorates the Inflammation State in Polycystic Ovary Syndrome Rats via Remodeling Gut Microbiota and Suppressing the TLR4/NF-κB Pathway

Background: Emerging evidence suggests that gut microbiota plays a vital role in the occurrence of multiple endocrine disorders including polycystic ovary syndrome (PCOS). Shaoyao-Gancao Decoction (SGD), a classical Chinese prescription, has been widely used in the treatment of PCOS for decades. In...

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Bibliographic Details
Main Authors: Zhuang-peng Chang, Gui-feng Deng, Yun-yun Shao, Ding Xu, Yi-nan Zhao, Yi-fan Sun, Shi-quan Zhang, Rui-gang Hou, Jun-jin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
polycystic ovary syndrome
shaoyao-gancao decoction
gut microbiota
gut barrier
TLR4/NF-κB pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.670054/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.670054/full

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