Nasal sensitization with ragweed pollen induces local-allergic-rhinitis-like symptoms in mice.

Recently, the concept of local allergic rhinitis (LAR) was established, namely rhinitis symptoms with local IgE production and negative serum antigen-specific IgE. However, the natural course of LAR development and the disease pathogenesis is poorly understood. This study investigated the pathophysi...

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Bibliographic Details
Main Authors: Yukinori Kato, Shoko Akasaki, Yoko Muto-Haenuki, Shigeharu Fujieda, Kazufumi Matsushita, Tomohiro Yoshimoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4132107?pdf=render