<em>Scutellaria barbata </em>D. Don<em> </em>Inhibits Tumor Angiogenesis via Suppression of Hedgehog Pathway in a Mouse Model of Colorectal Cancer

<em>Scutellaria barbata </em>D. Don<em> </em>Inhibits Tumor Angiogenesis via Suppression of Hedgehog Pathway in a Mouse Model of Colorectal Cancer

Angiogenesis, which plays a critical role during tumor development, is tightly regulated by the Sonic Hedgehog (SHH) pathway, which has been known to malfunction in many types of cancer. Therefore, inhibition of angiogenesis via modulation of the SHH signaling pathway has become very attractive for...

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Bibliographic Details
Main Authors: Jun Peng, Zhenfeng Hong, Aling Shen, Wei Xu, Qiaoyan Cai, Jiumao Lin, Lihui Wei
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:International Journal of Molecular Sciences
Subjects:
<em>Scutellaria barbata </em>D. Don
Chinese medicine
colorectal cancer
angiogenesis
SHH pathway
Online Access:http://www.mdpi.com/1422-0067/13/8/9419

Internet

http://www.mdpi.com/1422-0067/13/8/9419

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