Optimized Intracellular Staining Reveals Heterogeneous Cytokine Production Ability of Murine and Human Hematopoietic Stem and Progenitor Cells

Optimized Intracellular Staining Reveals Heterogeneous Cytokine Production Ability of Murine and Human Hematopoietic Stem and Progenitor Cells

Under stress conditions, hematopoietic stem and progenitor cells (HSPCs) can translate danger signals into a plethora of cytokine signals. These cytokines, or more precisely their combination, instruct HSPCs to modify the magnitude and composition of hematopoietic output in response to the threat, b...

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Bibliographic Details
Main Authors: Shufeng Luo, Huiling Lin, Lan Zhu, Hai-Tian Chen, Siqian Yang, Jinheng Li, Mingyu Liu, Limin Zheng, Chong Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
hematopoietic stem and progenitor cells
cytokine
flow cytometry
infection
tumor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.654094/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.654094/full

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