Hydrogen peroxide stimulates nuclear import of the POU homeodomain protein Oct-1 and its repressive effect on the expression of Cdx-2

<p>Abstract</p> <p>Background</p> <p>The ubiquitously expressed POU homeodomain protein Oct-1 serves as a sensor for stress induced by irradiation. We found recently that in pancreatic and intestinal endocrine cells, Oct-1 also functions as a sensor for cyclic AMP (cAMP...

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Bibliographic Details
Main Authors: Jin Tianru, Wang Peixiang
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/11/56