Screening of noise-induced hearing loss (NIHL)-associated SNPs and the assessment of its genetic susceptibility

Screening of noise-induced hearing loss (NIHL)-associated SNPs and the assessment of its genetic susceptibility

Abstract Background The aim of this study was to screen for noise-induced hearing loss (NIHL)-associated single nucleotide polymorphisms (SNPs) and to construct genetic risk prediction models for NIHL in a Chinese population. Methods Four hundred seventy-six subjects with NIHL and 476 matched contro...

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Bibliographic Details
Main Authors: Xuhui Zhang, Yaqin Ni, Yi Liu, Lei Zhang, Meibian Zhang, Xinyan Fang, Zhangping Yang, Qiang Wang, Hao Li, Yuyong Xia, Yimin Zhu
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Environmental Health
Subjects:
Genetic susceptibility
Noise-induced hearing loss (NIHL)
Single nucleotide polymorphisms (SNPs)
Genetic risk prediction
Genetic risk score (GRS)
Online Access:http://link.springer.com/article/10.1186/s12940-019-0471-9

Internet

http://link.springer.com/article/10.1186/s12940-019-0471-9

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