Mitochondrial genomic variation drives differential nuclear gene expression in discrete regions of Drosophila gene and protein interaction networks

Mitochondrial genomic variation drives differential nuclear gene expression in discrete regions of Drosophila gene and protein interaction networks

Abstract Background Mitochondria perform many key roles in their eukaryotic hosts, from integrating signaling pathways through to modulating whole organism phenotypes. The > 1 billion years of nuclear and mitochondrial gene co-evolution has necessitated coordinated expression of gene products fro...

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Bibliographic Details
Main Authors: Jim A. Mossman, Leann M. Biancani, David M. Rand
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Genomics
Subjects:
Mitonuclear
mtDNA
Haplotype
Gene expression
Systems biology
Online Access:http://link.springer.com/article/10.1186/s12864-019-6061-y

Internet

http://link.springer.com/article/10.1186/s12864-019-6061-y

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