Investigation of C-Cadherin mechanical properties by Molecular Dynamics

The mechanical stability of cell adhesion protein Cadherin with explicit model of water is studied by the method of molecular dynamics. The protein in apo-form and with the ions of different types (Ca2+, Mg2+, Na+, K+) was unfolding with a constant speed by applying the force to the ends. Eight inde...

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Bibliographic Details
Main Authors: Ilya Viatcheslavovich Lihachev, Oksana V. Galzitskaya, Nikolai K. Balabaev
Format: Article
Language:Russian
Published: Institute of Computer Science 2013-08-01
Series:Компьютерные исследования и моделирование
Subjects:
Online Access:http://crm.ics.org.ru/uploads/crmissues/crm_2013_4/13418.pdf