Estimation of Abbreviated Cyclosporine A Area under the Concentration-Time Curve in Allogenic Stem Cell Transplantation after Oral Administration

Measurements of Cyclosporine (CsA) systemic exposure permit its dose adjustment in allogenic stem cell transplantation recipients to prevent graft-versus-host disease. CsA LSSs were developed and validated from 60 ASCT patients via multiple linear regressions. All whole-blood samples were analyzed b...

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Bibliographic Details
Main Authors: Hanene ELjebari, Nadia Ben Fradj, Issam Salouage, Emna Gaies, Sameh Trabelsi, Nadia Jebabli, Mohamed Lakhal, Tarek Ben Othman, Anis Kouz
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2012/342701