Caspase cleavage sites in the human proteome: CaspDB, a database of predicted substrates.

Caspase cleavage sites in the human proteome: CaspDB, a database of predicted substrates.

Caspases are enzymes belonging to a conserved family of cysteine-dependent aspartic-specific proteases that are involved in vital cellular processes and play a prominent role in apoptosis and inflammation. Determining all relevant protein substrates of caspases remains a challenging task. Over 1500...

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Bibliographic Details
Main Authors: Sonu Kumar, Bram J van Raam, Guy S Salvesen, Piotr Cieplak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4201543?pdf=render

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