Nlrp3 Increases the Host’s Susceptibility to Tularemia

Nlrp3 Increases the Host’s Susceptibility to Tularemia

Francisella tularensis (F. tularensis) is a Gram-negative, intracellular bacterium and the causative agent of a fatal human disease known as tularemia. The CDC has classified F. tularensis as a Tier 1 Category A select agent based on its ease of aerosolization, low infectious dose, past use as a bio...

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Bibliographic Details
Main Authors: Ragavan V. Suresh, Elizabeth W. Bradley, Matthew Higgs, Vincenzo C. Russo, Maha Alqahtani, Wiehua Huang, Chandra Shekhar Bakshi, Meenakshi Malik
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Microbiology
Subjects:
Francisella tularensis
Nlrp3
inflammasome
pro-inflammatory cytokines
virulence
IL-1β
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.725572/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.725572/full

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