Tissue Microenvironment Modulates CXCR4 Expression and Tumor Metastasis in Neuroblastoma

Neuroblastoma (NB) is derived from intrinsic migratory neural crest cells and has a high potential for distant metastasis. Growing evidence has implicated chemokine receptors, especially CXCR4, which normally control immune and inflammatory cell migration, as having important roles in tumor progres...

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Bibliographic Details
Main Authors: Libo Zhang, Herman Yeger, Bikul Das, Meredith S. Irwin, Sylvain Baruchel
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607801060