Limiting of the innate immune response by SF3A-dependent control of MyD88 alternative mRNA splicing.

Controlling infectious disease without inducing unwanted inflammatory disease requires proper regulation of the innate immune response. Thus, innate immunity needs to be activated when needed during an infection, but must be limited to prevent damage. To accomplish this, negative regulators of innat...

Full description

Bibliographic Details
Main Authors: Lesly De Arras, Scott Alper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3812059?pdf=render