A role for pancreatic beta-cell secretory hyperresponsiveness in catch-up growth hyperinsulinemia: <it>Relevance to thrifty catch-up fat phenotype and risks for type 2 diabetes</it>

<p>Abstract</p> <p>Current notions about mechanisms by which catch-up growth predisposes to later type 2 diabetes center upon those that link hyperinsulinemia with an accelerated rate of fat deposition (catch-up fat). Using a rat model of semistarvation-refeeding in which catch-up...

Full description

Bibliographic Details
Main Authors: Montani Jean-Pierre, Gjinovci Asllan, de Andrade Paula B, Casimir Marina, Maechler Pierre, Dulloo Abdul G
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Nutrition & Metabolism
Online Access:http://www.nutritionandmetabolism.com/content/8/1/2