BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor

BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor

Low-density lipoprotein receptor (LDLR) in hepatocytes plays a key role in plasma clearance of circulating LDL and in whole body cholesterol homeostasis. The trafficking of LDLR is highly regulated in clathrin-dependent endocytosis, endosomal recycling and lysosomal degradation. Current studies focu...

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Bibliographic Details
Main Authors: Chang Zhang, Chanjuan Hao, Guanghou Shui, Wei Li
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
LDL receptor
endosomal recycling
microtubules
kinesins
BLOS1
dyslipidemia
Online Access:https://elifesciences.org/articles/58069

Internet

https://elifesciences.org/articles/58069

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