Reassessing the Role of Type II Toxin-Antitoxin Systems in Formation of Escherichia coli Type II Persister Cells

Reassessing the Role of Type II Toxin-Antitoxin Systems in Formation of Escherichia coli Type II Persister Cells

Persistence is a reversible and low-frequency phenomenon allowing a subpopulation of a clonal bacterial population to survive antibiotic treatments. Upon removal of the antibiotic, persister cells resume growth and give rise to viable progeny. Type II toxin-antitoxin (TA) systems were assumed to pla...

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Bibliographic Details
Main Authors: Frédéric Goormaghtigh, Nathan Fraikin, Marta Putrinš, Thibaut Hallaert, Vasili Hauryliuk, Abel Garcia-Pino, Andreas Sjödin, Sergo Kasvandik, Klas Udekwu, Tanel Tenson, Niilo Kaldalu, Laurence Van Melderen
Format: Article
Language:English
Published: American Society for Microbiology 2018-06-01
Series:mBio
Subjects:
RelE
YoeB
ampicillin
single cell
Online Access:https://doi.org/10.1128/mBio.00640-18

Internet

https://doi.org/10.1128/mBio.00640-18

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