Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer’s disease pathology and clinical disease progression

Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer’s disease pathology and clinical disease progression

Abstract Background To assess the performance of plasma neurofilament light (NfL) and phosphorylated tau 181 (p-tau181) to inform about cerebral Alzheimer’s disease (AD) pathology and predict clinical progression in a memory clinic setting. Methods Plasma NfL and p-tau181, along with established cer...

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Bibliographic Details
Main Authors: Christopher Clark, Piotr Lewczuk, Johannes Kornhuber, Jonas Richiardi, Bénédicte Maréchal, Thomas K. Karikari, Kaj Blennow, Henrik Zetterberg, Julius Popp
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Alzheimer’s Research & Therapy
Subjects:
Biomarkers
Plasma
Alzheimer’s
Neurofilament light
p-tau181
Online Access:https://doi.org/10.1186/s13195-021-00805-8

Internet

https://doi.org/10.1186/s13195-021-00805-8

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