Social Stimulus Causes Aberrant Activation of the Medial Prefrontal Cortex in a Mouse Model With Autism-Like Behaviors

Social Stimulus Causes Aberrant Activation of the Medial Prefrontal Cortex in a Mouse Model With Autism-Like Behaviors

Autism spectrum disorder (ASD) is a highly prevalent and genetically heterogeneous brain disorder. Developing effective therapeutic interventions requires knowledge of the brain regions that malfunction and how they malfunction during ASD-relevant behaviors. Our study provides insights into brain re...

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Bibliographic Details
Main Authors: Antonella Pirone, Jonathan M. Alexander, Jenny B. Koenig, Denise R. Cook-Snyder, Medha Palnati, Robert J. Wickham, Lillian Eden, Neha Shrestha, Leon Reijmers, Thomas Biederer, Klaus A. Miczek, Chris G. Dulla, Michele H. Jacob
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
autism
social behavior
β-catenin
APC
parvalbumin
medial prefrontal cortex
Online Access:https://www.frontiersin.org/article/10.3389/fnsyn.2018.00035/full

Internet

https://www.frontiersin.org/article/10.3389/fnsyn.2018.00035/full

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