Gene Manipulation Strategies to Identify Molecular Regulators of Axon Regeneration in the Central Nervous System

Limited axon regeneration in the injured adult mammalian central nervous system (CNS) usually results in irreversible functional deficits. Both the presence of extrinsic inhibitory molecules at the injury site and the intrinsically low capacity of adult neurons to grow axons are responsible for the...

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Bibliographic Details
Main Authors: Vinicius T. Ribas, Marcos R. Costa
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00231/full