Increased extracellular fluid is associated with white matter fiber degeneration in CADASIL: in vivo evidence from diffusion magnetic resonance imaging

Increased extracellular fluid is associated with white matter fiber degeneration in CADASIL: in vivo evidence from diffusion magnetic resonance imaging

Abstract Background White matter hyperintensities (WMHs) are one of the hallmarks of cerebral small vessel disease (CSVD), but the pathological mechanisms underlying WMHs remain unclear. Recent studies suggest that extracellular fluid (ECF) is increased in brain regions with WMHs. It has been hypoth...

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Bibliographic Details
Main Authors: Xinfeng Yu, Xinzhen Yin, Hui Hong, Shuyue Wang, Yeerfan Jiaerken, Fan Zhang, Ofer Pasternak, Ruiting Zhang, Linglin Yang, Min Lou, Minming Zhang, Peiyu Huang
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Fluids and Barriers of the CNS
Subjects:
White matter
Extracellular fluid
Cerebral small vessel diseases
CADASIL
MRI
Diffusion-weighted imaging
Online Access:https://doi.org/10.1186/s12987-021-00264-1

Internet

https://doi.org/10.1186/s12987-021-00264-1

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