Sex specific gene regulation and expression QTLs in mouse macrophages from a strain intercross.

A powerful way to identify genes for complex traits it to combine genetic and genomic methods. Many trait quantitative trait loci (QTLs) for complex traits are sex specific, but the reason for this is not well understood.RNA was prepared from bone marrow derived macrophages of 93 female and 114 male...

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Bibliographic Details
Main Authors: Jeffrey M Bhasin, Enakshi Chakrabarti, Dao-Quan Peng, Aneesh Kulkarni, Xi Chen, Jonathan D Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2174529?pdf=render