Re-expression of CD14 in Response to a Combined IL-10/TLR Stimulus Defines Monocyte-Derived Cells With an Immunoregulatory Phenotype

Re-expression of CD14 in Response to a Combined IL-10/TLR Stimulus Defines Monocyte-Derived Cells With an Immunoregulatory Phenotype

Interleukin 10 is a central regulator of the antigen-presenting function of myeloid cells. It exerts immunomodulatory effects in vivo and induces a regulatory phenotype in monocyte-derived cells in vitro. We analyzed phenotype and function of monocytic cells in vitro in relation to the cytokine mili...

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Bibliographic Details
Main Authors: Sören Krakow, Marie L. Crescimone, Charlotte Bartels, Verena Wiegering, Matthias Eyrich, Paul G. Schlegel, Matthias Wölfl
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
regulatory dendritic cells
MDSC
monocyte-derived DC
IL-10
macrophages
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01484/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01484/full

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