Arterially perfused neurosphere-derived cells distribute outside the ischemic core in a model of transient focal ischemia and reperfusion in vitro.

BACKGROUND: Treatment with neural stem cells represents a potential strategy to improve functional recovery of post-ischemic cerebral injury. The potential benefit of such treatment in acute phases of human ischemic stroke depends on the therapeutic viability of a systemic vascular delivery route. I...

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Bibliographic Details
Main Authors: Chiara Pastori, Laura Librizzi, Gian Luca Breschi, Cristina Regondi, Carolina Frassoni, Ferruccio Panzica, Simona Frigerio, Maurizio Gelati, Eugenio Parati, Maria Grazia De Simoni, Marco de Curtis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2453234?pdf=render