DNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cells.

DNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cells.

The potential for human disease treatment using human pluripotent stem cells, including embryonic stem cells and induced pluripotent stem cells (iPSCs), also carries the risk of added genomic instability. Genomic instability is most often linked to DNA repair deficiencies, which indicates that scree...

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Bibliographic Details
Main Authors: Li Z Luo, Sailesh Gopalakrishna-Pillai, Stephanie L Nay, Sang-Won Park, Steven E Bates, Xianmin Zeng, Linda E Iverson, Timothy R O'Connor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3295811?pdf=render

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http://europepmc.org/articles/PMC3295811?pdf=render

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