Preventing DNA over-replication: a Cdk perspective

<p>Abstract</p> <p>The cell cycle is tightly controlled to ensure that replication origins fire only once per cycle and that consecutive S-phases are separated by mitosis. When controls fail, DNA over-replication ensues: individual origins fire more than once per S-phase (re-replic...

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Bibliographic Details
Main Author: Porter Andrew CG
Format: Article
Language:English
Published: BMC 2008-01-01
Series:Cell Division
Online Access:http://www.celldiv.com/content/3/1/3