Structural Development Studies of Subtype-Selective Ligands for Peroxisome Proliferator-Activated Receptors (PPARs) Based on the 3,4-Disubstituted Phenylpropanoic Acid Scaffold as a Versatile Template

Improvements in our understanding of the functions of the nuclear receptor peroxisome proliferator-activated receptor (PPAR) subtypes as pleiotropic regulators of biological responses, including lipid, lipoprotein, glucose homeostasis, inflammation, differentiation and proliferation of various cance...

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Bibliographic Details
Main Authors: Hiroyuki Miyachi, Yuichi Hashimoto
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2008/689859