Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model

Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model

Protein palmitoylation and depalmitoylation alter protein function. This post-translational modification is critical for synaptic transmission and plasticity. Mutation of the depalmitoylating enzyme palmitoyl-protein thioesterase 1 (PPT1) causes infantile neuronal ceroid lipofuscinosis (CLN1), a ped...

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Bibliographic Details
Main Authors: Kevin P Koster, Walter Francesconi, Fulvia Berton, Sami Alahmadi, Roshan Srinivas, Akira Yoshii
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-04-01
Series:eLife
Subjects:
NMDA
lipofuscinosis
palmitoylation
neurodevelopment
depalmitoylation
Online Access:https://elifesciences.org/articles/40316

Internet

https://elifesciences.org/articles/40316

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