A novel derivative of picolinic acid induces endoplasmic reticulum stress-mediated apoptosis in human non-small cell lung cancer cells: synthesis, docking study, and anticancer activity
Thirteen new derivatives of picolinic acid (4–7) were designed and synthesized from the starting parent molecule, picolinic acid. The new compounds were characterized by ATR-FTIR, 1HNMR, and CHNS analysis. A molecular docking study was performed to evaluate the binding affinity of the synthesized co...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pensoft Publishers
2021-09-01
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| Series: | Pharmacia |
| Online Access: | https://pharmacia.pensoft.net/article/70654/download/pdf/ |