Anti-Inflammatory Activity of A Polyphenolic Extract from <i>Arabidopsis thaliana</i> in In Vitro and In Vivo Models of Alzheimer’s Disease

Anti-Inflammatory Activity of A Polyphenolic Extract from <i>Arabidopsis thaliana</i> in In Vitro and In Vivo Models of Alzheimer’s Disease

Alzheimer&#8217;s disease (AD) is the most common neurodegenerative disorder and the primary form of dementia in the elderly. One of the main features of AD is the increase in amyloid-beta (A&#946;) peptide production and aggregation, leading to oxidative stress, neuroinflammation and neurod...

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Bibliographic Details
Main Authors: Roberto Mattioli, Antonio Francioso, Maria d’Erme, Maurizio Trovato, Patrizia Mancini, Lucia Piacentini, Assunta Maria Casale, Ludger Wessjohann, Roberta Gazzino, Paolo Costantino, Luciana Mosca
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Arabidopsis thaliana</i>
amyloid beta
polyphenols
Alzheimer’s disease
BV2 cells
interleukins
Nrf2
NF-κB
Online Access:https://www.mdpi.com/1422-0067/20/3/708

Internet

https://www.mdpi.com/1422-0067/20/3/708

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