Gut microbiota remodeling reverses aging-associated inflammation and dysregulation of systemic bile acid homeostasis in mice sex-specifically

Gut microbiota remodeling reverses aging-associated inflammation and dysregulation of systemic bile acid homeostasis in mice sex-specifically

Aging is usually characterized with inflammation and disordered bile acids (BAs) homeostasis, as well as gut dysbiosis. The pathophysiological changes during aging are also sexual specific. However, it remains unclear about the modulating process among gut microbiota, BA metabolism, and inflammation...

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Bibliographic Details
Main Authors: Junli Ma, Ying Hong, Ningning Zheng, Guoxiang Xie, Yuanzhi Lyu, Yu Gu, Chuchu Xi, Linlin Chen, Gaosong Wu, Yue Li, Xin Tao, Jing Zhong, Zhenzhen Huang, Wenbin Wu, Lin Yuan, Min Lin, Xiong Lu, Weidong Zhang, Wei Jia, Lili Sheng, Houkai Li
Format: Article
Language:English
Published: Taylor & Francis Group 2020-09-01
Series:Gut Microbes
Subjects:
aging
inflammation
gut microbiota
bile acid composition
sex difference
Online Access:http://dx.doi.org/10.1080/19490976.2020.1763770

Internet

http://dx.doi.org/10.1080/19490976.2020.1763770

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