Diagnostic value of methylated human telomerase reverse transcriptase (hTERT) in human cancers: a meta-analysis

Human telomerase reverse transcriptase (hTERT) plays a critical role in the pathogenesis of human malignancies. Overexpression of hTERT is essential in controlling the propagation of cancer cells. The CpG island located at hTERT promoter region is subjected to methylation modification in human cance...

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Bibliographic Details
Main Authors: Wei eGao, Yuan eShi, Wei eLiu, Wei-Yin eLin, Chia-Ching (Josh) eWu, Jimmy Yu-Wai eChan, Thian-Sze eWong
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00296/full