An engineered bacterium auxotrophic for an unnatural amino acid: a novel biological containment system

Biological containment is a genetic technique that programs dangerous organisms to grow only in the laboratory and to die in the natural environment. Auxotrophy for a substance not found in the natural environment is an ideal biological containment. Here, we constructed an Escherichia coli strain th...

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Bibliographic Details
Main Author: Yusuke Kato
Format: Article
Language:English
Published: PeerJ Inc. 2015-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/1247.pdf