Cholesterol lowering modulates T cell function in vivo and in vitro.

The lipid milleu exacerbates the inflammatory response in atherosclerosis but its effect on T cell mediated immune response has not been fully elucidated. We hypothesized that lipid lowering would modulate T cell mediated immune function.T cells isolated from human PBMC or splenic T cells from apoE-...

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Bibliographic Details
Main Authors: Kuang-Yuh Chyu, Wai Man Lio, Paul C Dimayuga, Jianchang Zhou, Xiaoning Zhao, Juliana Yano, Portia Trinidad, Tomoyuki Honjo, Bojan Cercek, Prediman K Shah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3960213?pdf=render