Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by an exacerbated fibrotic response. Although molecular and cellular determinants involved in the onset and progression of this devastating disease are largely unknown, an aberrant remodeling of the pulmonary vasculature app...

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Bibliographic Details
Main Authors: Alessandro Giuseppe Fois, Anna Maria Posadino, Roberta Giordo, Annalisa Cossu, Abdelali Agouni, Nasser Moustafa Rizk, Pietro Pirina, Ciriaco Carru, Angelo Zinellu, Gianfranco Pintus
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/2639081