In vitro murine leukemia retroviral integration and structure fluctuation of target DNA.

Integration of the retroviral genome into host DNA is a critical step in the life cycle of a retrovirus. Although assays for in vitro integration have been developed, the actual DNA sequences targeted by murine leukemia retrovirus (MLV) during in vitro reproduction are unknown. While previous studie...

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Bibliographic Details
Main Authors: Tatsuaki Tsuruyama, Weizhi Liu, Kenichi Yoshikawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3279379?pdf=render