Using the Spleen as an In Vivo Systemic Immune Barometer Alongside Osteosarcoma Disease Progression and Immunotherapy with α-PD-L1

Indications for immunotherapies are still unclear, and there is a great need for real-time patient immune status monitoring. In this study, we confirmed that the local and systemic immune profiles of an orthotopic osteosarcoma model with or without luciferase transfection were statistically equivale...

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Bibliographic Details
Main Authors: Justin E. Markel, Jabeen Noore, Eric J. Emery, Harley J. Bobnar, Eugenie S. Kleinerman, Brock A. Lindsey
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/2018/8694397