DNAJA3/Tid1 Is Required for Mitochondrial DNA Maintenance and Regulates Migration and Invasion of Human Gastric Cancer Cells

DNAJA3/Tid1 Is Required for Mitochondrial DNA Maintenance and Regulates Migration and Invasion of Human Gastric Cancer Cells

Background: Gastric cancer is a common health issue. Deregulated cellular energetics is regarded as a cancer hallmark and mitochondrial dysfunction might contribute to cancer progression. Tid1, a mitochondrial co-chaperone, may play a role as a tumor suppressor in various cancers, but the role of Ti...

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Bibliographic Details
Main Authors: Sheng-Fan Wang, Kuo-Hung Huang, Wei-Chuan Tseng, Jeng-Fan Lo, Anna Fen-Yau Li, Wen-Liang Fang, Chian-Feng Chen, Tien-Shun Yeh, Yuh-Lih Chang, Yueh-Ching Chou, Hung-Hsu Hung, Hsin-Chen Lee
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
gastric cancer
Tid1
mitochondria
cancer progression
galectin-7
MMP-9
Online Access:https://www.mdpi.com/2072-6694/12/11/3463

Internet

https://www.mdpi.com/2072-6694/12/11/3463

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