PET Imaging of Integrin Positive Tumors Using 18F Labeled Knottin Peptides

<p><i>Purpose</i>: Cystine knot (knottin) peptides, engineered to bind with high affinity to integrin receptors, have shown promise as molecular imaging agents in living subjects. The aim of current study was to evaluate tumor uptake and <i>in vivo</i> biodistribution o...

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Bibliographic Details
Main Author: Shuanglong Liu, Hongguang Liu, Gang Ren, Richard H. Kimura, Jennifer R. Cochran, Zhen Cheng
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:Theranostics
Online Access:http://www.thno.org/v01p0403.htm