Ulmus parvifolia Modulates Platelet Functions and Inhibits Thrombus Formation by Regulating Integrin αIIbβ3 and cAMP Signaling

Ulmus parvifolia Modulates Platelet Functions and Inhibits Thrombus Formation by Regulating Integrin αIIbβ3 and cAMP Signaling

BackgroundThe prevalence of cardiovascular diseases (CVDs) is increasing at a high rate, and the available treatment options, sometimes, have complications which necessitates the need to develop safer and efficacious approaches. Ethnomedicinal applications reportedly reduce CVD risk. Ulmus parvifoli...

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Bibliographic Details
Main Authors: Muhammad Irfan, Hyuk-Woo Kwon, Dong-Ha Lee, Jung-Hae Shin, Heung Joo Yuk, Dong-Seon Kim, Seung-Bok Hong, Sung-Dae Kim, Man Hee Rhee
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
U. parvifolia
ethnomedicine
platelet
integrin αIIbβ3
cyclic-AMP
VASPser157
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00698/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.00698/full

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