Nonspecific Effects of the Selective κ-Opioid Receptor AgonistU-50,488H on Dopamine Uptake and Release in PC12 Cells

ABSTRACT: κ-Opioid receptor agonists decrease the levels of extracellular dopamine in vivo and in vitro. However, the mechanism(s) underlying these actions are unclear. The objective of this study was to distinguish between an effect of the selective κ-opioid receptor agonist U-50,488H ((trans-(±)-3...

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Bibliographic Details
Main Authors: Nuannoi Chudapongse, Seong-Youl Kim, Robert E. Kramer, Ing K. Ho
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319326040