<i>AKNA</i> Frameshift Variant in Three Dogs with Recurrent Inflammatory Pulmonary Disease

<i>AKNA</i> Frameshift Variant in Three Dogs with Recurrent Inflammatory Pulmonary Disease

We investigated three related Rough Collies with recurrent inflammatory pulmonary disease. The clinical symptoms were similar to primary ciliary dyskinesia (PCD). However, the affected dogs did not carry any known pathogenic PCD variants. Pedigree analysis suggested a recessive mode of inheritance....

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Bibliographic Details
Main Authors: Petra Hug, Linda Anderegg, Alexandra Kehl, Vidhya Jagannathan, Tosso Leeb
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Genes
Subjects:
<i>Canis lupus familiaris</i>
dog
whole genome sequence
animal model
AT-hook transcription factor
immunology
inflammation
infection
rare disease
precision medicine
Online Access:https://www.mdpi.com/2073-4425/10/8/567

Internet

https://www.mdpi.com/2073-4425/10/8/567

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