Rapid mapping of chromosomal breakpoints: from blood to BAC in 20 days.

Structural chromosome aberrations and associated segmental or chromosomal aneusomies are major causes of reproductive failure in humans. Despite the fact that carriers of reciprocal balanced translocation often have no other clinical symptoms or disease, impaired chromosome homologue pairing in meio...

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Bibliographic Details
Main Authors: Mei Wang, Adolf Baumgartner, Jingly F Weier, Johnson Kwan, Chun-Mei Lu, Tomas Escudero, Santiago MunnĂŠ, Heinz-Ulrich G Weier
Format: Article
Language:English
Published: Via Medica 2010-02-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4336