Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis

<p>Abstract</p> <p>Background</p> <p>High-throughput genomics has enabled the global mapping of genetic interactions based on the phenotypic impact of combinatorial genetic perturbations. An important next step is to understand how these networks are dynamically remodel...

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Bibliographic Details
Main Authors: Batenchuk Cory, Tepliakova Lioudmila, Kærn Mads
Format: Article
Language:English
Published: BMC 2010-09-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/11/493