Codon Pair Bias Is a Direct Consequence of Dinucleotide Bias
Codon pair bias is a remarkably stable characteristic of a species. Although functionally uncharacterized, robust virus attenuation was achieved by recoding of viral proteins using underrepresented codon pairs. Because viruses replicate exclusively inside living cells, we posited that their codon pa...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-01-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715014242 |