Mesenchymal stromal cell secreted sphingosine 1-phosphate (S1P) exerts a stimulatory effect on skeletal myoblast proliferation.

Bone-marrow-derived mesenchymal stromal cells (MSCs) have the potential to significantly contribute to skeletal muscle healing through the secretion of paracrine factors that support proliferation and enhance participation of the endogenous muscle stem cells in the process of repair/regeneration. Ho...

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Main Authors: Chiara Sassoli, Alessia Frati, Alessia Tani, Giulia Anderloni, Federica Pierucci, Francesca Matteini, Flaminia Chellini, Sandra Zecchi Orlandini, Lucia Formigli, Elisabetta Meacci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4181304?pdf=render