Neuroprotection mediated by ST266 requires full complement of proteins secreted by amnion-derived multipotent progenitor cells.

ST266 is the biological secretome of cultured Amnion-derived Multipotent Progenitor cells containing multiple growth factors and cytokines. While intranasally-administered ST266 improves the phenotype in experimental optic neuritis, specific ST266 components mediating these effects are not known. We...

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Bibliographic Details
Main Authors: Keirnan Willett, Reas S Khan, Kimberly Dine, Howard Wessel, Ziv Z Kirshner, Jodie L Sauer, Ashley Ellis, Larry R Brown, Kenneth S Shindler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0243862