Ototoxicity and otoprotection in the inner ear of guinea pigs using gentamicin and amikacin: ultrastructural and functional aspects

Summary: Ototoxicity is still a challenge to medicine. The discovery of self-protecting endogenous mechanisms of the outer hair cells associated with their functional and ultra-structural assessment methods has opened new horizons in the understanding and controlling of these mechanisms. Aim: this p...

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Bibliographic Details
Main Authors: Thomaz José Marra de Aquino, José Antônio Apparecido de Oliveira, Maria Rossato
Format: Article
Language:English
Published: Elsevier 2008-11-01
Series:Brazilian Journal of Otorhinolaryngology
Online Access:http://www.sciencedirect.com/science/article/pii/S1808869415301440