Dual Carbonic Anhydrase IX/XII Inhibitors and Carbon Monoxide Releasing Molecules Modulate LPS-Mediated Inflammation in Mouse Macrophages

Dual Carbonic Anhydrase IX/XII Inhibitors and Carbon Monoxide Releasing Molecules Modulate LPS-Mediated Inflammation in Mouse Macrophages

Low concentrations of carbon monoxide (CO) were reported to exhibit anti-inflammatory effects when administered in cells by suitable chemotypes such as CO releasing molecules (CO-RMs). In addition, the pH-modulating abilities of specific carbonic anhydrase isoforms played a crucial role in different...

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Bibliographic Details
Main Authors: Emanuela Berrino, Simone Carradori, Andrea Angeli, Fabrizio Carta, Claudiu T. Supuran, Paolo Guglielmi, Cecilia Coletti, Roberto Paciotti, Helmut Schweikl, Francesca Maestrelli, Elisabetta Cerbai, Marialucia Gallorini
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Antioxidants
Subjects:
CO-RMs
carbonic anhydrase inhibitor
cobalt
macrophages
inflammation
carbon monoxide
Online Access:https://www.mdpi.com/2076-3921/10/1/56

Internet

https://www.mdpi.com/2076-3921/10/1/56

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