In vitro identification of novel plasminogen-binding receptors of the pathogen Leptospira interrogans.

In vitro identification of novel plasminogen-binding receptors of the pathogen Leptospira interrogans.

BACKGROUND: Leptospirosis is a multisystem disease caused by pathogenic strains of the genus Leptospira. We have reported that Leptospira are able to bind plasminogen (PLG), to generate active plasmin in the presence of activator, and to degrade purified extracellular matrix fibronectin. METHODOLOGY...

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Bibliographic Details
Main Authors: Monica L Vieira, Marina V Atzingen, Tatiane R Oliveira, Rosane Oliveira, Daniel M Andrade, Silvio A Vasconcellos, Ana L T O Nascimento
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2889836?pdf=render

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http://europepmc.org/articles/PMC2889836?pdf=render

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